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Spectrum of complicated pulmonary infections in 152 AIDS patients

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Author:
No author available
Journal Title:
International Journal of Virology
Issue:
3
DOI:
10.3760/cma.j.issn.1673-4092.2024.03.008
Key Word:
艾滋病;肺部感染;疾病谱;Acquired immunodeficiency syndrome;Pulmonary infection;Disease spectrum

Abstract: Objective:To investigate the characteristics of the spectrum of pulmonary infections in AIDS patients so as to provide ideas for clinical diagnosis.Methods:The clinical data of 152 AIDS patients complicated with pulmonary infections were collected from the inpatient section of Beijing Ditan Hospital from May 2018 to August 2023, and SPSS 25.0 was used for statistical analysis.Results:The spectrum of pulmonary infections among 152 AIDS patients were pneumocystis pneumonia (59.9%), bacterial pneumonia (55.9%), cytomegalovirus pneumonia (25.7%), pulmonary tuberculosis (23.7%), fungal pneumonia (22.4%), and nontuberculous mycobacterial infection (6.6%), successively. There were 54 cases (35.5%) of pulmonary infection by single pathogen and 98 cases (64.5%) by multiple pathogens. The proportions of multiple pathogen infection were 66.3%, 25.5%, and 8.2% in patients with CD4 cell counts <50 cells/μL, 50-200 cells/μL, and >200 cells/μL, respectively.Conclusions:The AIDS inpatients complicated with pulmonary infections in Beijing Ditan Hospital were mainly pneumocystis pneumonia and bacterial pneumonia. The common type of pulmonary infection was mixed infection, and the occurrence of multiple pathogen infection was closely related to CD4 cell counts.

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